Janssen Research & Development, L.L.C., a division of Johnson & Johnson s Family of Companies is recruiting for an Associate Scientist, In Vivo Cancer Pharmacology, located in Spring House, PA.
At the Janssen Pharmaceutical Companies of Johnson & Johnson, we are working to create a world without disease. Transforming lives by finding new and better ways to prevent, intercept, treat and cure disease inspires us. We bring together the best minds and pursue the most promising science.
We are Janssen. We collaborate with the world for the health of everyone in it. Learn more at www.janssen.com and follow us @JanssenGlobal. Janssen Research & Development, LLC is part of the Janssen Pharmaceutical Companies.
The In Vivo Associate Scientist will join the in vivo group efforts in the characterization and development of small molecules and biologics including those that function as immune modulators for the treatment of cancer. S/he will be responsible for contributing to the ex vivo and in vivo studies for multiple research programs across the different stages of pre-clinical drug discovery. His/her responsibilities include the design, execution and interpretation of in vivo studies for the validation and characterization of targets or therapeutic agents in the area of oncology and tumor immunology. Specifically, the candidate will establish and perform in vivo model development, target inhibition, efficacy, mechanism of action, and pharmacokinetic/pharmacodynamics (PK/PD) biomarker studies, and will evaluate the influence of dose, schedule and therapeutic combinations in various cancer models.
S/he will demonstrate their ability to design, perform, interpret and report complex in vivo preclinical cancer models.
S/he will be proficient in in vivo experimentation, including standard methods of tumor implantation and dosing, proper handling of chemotherapeutics, tumor measurement, health monitoring, and data collection and analysis.
Contribute to ex vivo analysis of tumor cells or immune cells by FACS, IHC and ELISA.
S/he will demonstrate the ability to analyze and present data in a clear presentation ready format.
S/he will demonstrate the ability to manage multiple in vivo experiments simultaneously.
The candidate will demonstrate the ability to contribute on various projects outside of his/her own, collaborate with stakeholders from all relevant functions, and keep up-to-date in the literature related to his/her field.
S/he will act as an expert resource on project teams and demonstrate clear and professional verbal and written communication.
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