The Broad Institute seeks an enthusiastic Lab Assistant to support the patient-derived cancer cell model development at scale for the Cancer Cell Line Factory (CCLF) project (www.broadinstitute.org/cellfactory) . This position affords the exciting opportunity to be part of a new and rapidly growing research effort between DFCI and the Broad Institute aiming to create hundreds of new models of cancer each year directly from patient samples, with full genomic and clinical characterization, to fuel the study of cancer dependencies at scale. The Lab Assistant is responsible for the biospecimen sample acquisition, sample kit preparation, and viable sample cryopreservation. The candidate must be able to effectively work with the project coordinator, project managers, In-Lab manager, and scientists, perform operation protocols for scientific and regulatory needs, and review/analyze reports of executed testing in real time. The candidate must also communicate delays and risks to the CCLF Team Manager and management on a regular basis. The candidate is also responsible for executing developed plans for the contracting deliverable, considering timelines and schedules, risk mitigation and mission priorities. The candidate will work closely with the In-Lab manager and the Team. Manager to develop metric parameters to evaluate and monitor the performance of biospecimen process and cryopreservation workflow.
Responsible for biospecimen receiving process, biospecimen dissociation/enrichment, and sample cryopreservation on a daily basis
Interacts directly with the In-Lab Manager, the Team Manager and scientists regarding lab services in a helpful and professional manner in all interactions
Follows established protocols and procedures to prepare and sample acquisition/delivery kit, solutions, reagents, and labeled units
Responsible for the occasional weekend/holidays sample pickup
Communicates results of quality testing effectively.
Delivers sample kit, solutions, reagents and labeled units according to the project needs and records transactions accurately in the tracking/documentation systems
Expected to manage inventory of valuable purchased chemicals and complex kits
Will be expected to adjust to new processes and technologies as required
Encouraged to suggest improvements to current workflow processes
Other tasks as required so those goals are met
BS in molecular biology, biochemistry, bioengineering, biomedical engineering, chemical engineering, or a closely related discipline is required.
Experience with maintaining mammalian cell culture, optimizing research protocols and assays are plus.
Must be able to multitask while maintaining attention to detail
Must be receptive to instruction and able to follow written protocols; should be interested in learning new processes
Ability to work independently and as part of a team
Good communication skills and a desire to work in a fast-paced, multicultural environment
Willing and able to pick samples up on few holidays or weekends (FedEx Office, Harvard sq)
The Broad Institute will not offer visa sponsorship for this opportunity.
EOE / Minorities / Females / Protected Veterans / Disabilities
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