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Job ID : 27149

Location : Ann Arbor, MI

Company Name : TekWissen

Job Type : Contract

Industry : Biotech/Pharmaceutical

Salary : $30 - $40  per hour

No. of Positions : 2-4

Required Skills : Cell Therapy Process Development, CRISPR, Cell And Gene Therapy

Benefits : No benefits are available

Job Description :
  • This position requires a talented and highly motivated scientist to immediately support a high priority project within the Cell and Gene Therapy R&D team. 
  • The role will focus on the optimization and development of specific protocols for genetic engineering of t-cells, NK cells and/or hematopoietic stem cells using CRISPR gene-editing tools and new delivery technology platforms.   
  • The ideal candidate will have knowledge and experience in cell therapy process development. 
  • They will also be able to troubleshoot and integrate instruments across workflows for large-scale culture needs.  Additionally, an adaptable and flexible scientist that can work quickly in a fast-paced environment is highly preferred. 

Primary Responsibilities 

  • Critically design, plan and independently execute experiments while adhering to project requirements and deadlines 
  • Optimize protocols for genetic modification of immune and stem cells with CRISPR based tools in support of customer needs 
  • Setup and perform complex flow cytometry characterization assays to identify specific cell populations 
  • Maintain detailed, organized notebook and experiment write-ups that can be quickly referenced and referred to 
  • Utilize Design of Experiment to promptly analyze assay results and creatively prepare presentations to communicate scientific findings, conclusions and next steps 

Knowledge, Skills, Abilities 

  • Demonstrate a sense of urgency, strong drive and can-do attitude to take on new tasks with initiative and intensity 
  • Excellent verbal and written communication skills 
  • Highly developed presentation skills to communicate results and needs to both internal and external team members 
  • Aseptic cell culture of primary cells and/or immune cell experience is required 
  • Experience with automated isolation/purification of various primary blood cell types 
  • CRISPR based assay development for both knock-out and knock-in optimization 
  • Experience with Attune NxT Flow Cytometer is preferred but not required 
  • Education Requirements 
  • PhD in cellular biology, immunology or another relevant discipline with 1-2 years of industry experience, or 
  • M.S. degree in relevant discipline with 3-4 years of industry experience 

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