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Scientist, Potency Assays

Seattle Genetics, Inc. – Bothell, WA

Summary:

This position will focus on the development of biological assays to support the development and characterization of Seattle Genetics (SGEN) antibodies and antibody-drug conjugates (ADCs). The successful candidate will work closely with various functional areas within Biological Development and Manufacturing and with Quality Control. The successful candidate will develop, qualify and implement potency assays to support process development activities, drug product release and regulatory filings.


Responsibilities:

  • Develop, qualify and implement potency assays (cytotoxicity, binding, effector function, immunological and other assays) to support early- and late-phase product and process development
  • Transfer potency assays to QC GMP group
  • Represent the group as a lead on technical, CMC strategy and other cross-functional teams; develop and lead group initiatives
  • Write technical reports and CMC documents to support regulatory filings
  • Supervise and mentor research associate(s)


Qualifications:

  • PhD. in Immunology, Molecular Biology, Cancer Biology, Microbiology, Bioengineering or related discipline. 1-2 years industry experience preferred
  • Demonstrated technical expertise in immunological and general cell-based assays, ELISAs, homogeneous binding assays (AlphaLISA and TR-FRET assays), Octet, FACS, tissue culture and molecular biology techniques
  • Experience in the use of live cell imaging systems is strongly desired
  • Experience with use of high-throughput liquid-handling systems
  • Candidate must be driven, high-motivated and be able to work in a fast-paced, matrixed environment
  • Strong interpersonal skills and the ability to work in a multi-disciplinary team environment
  • Excellent oral and written communication skills
  • Experience with regulatory submissions preferred
  • Creative, independent, well-organized and solution-oriented
  • Supervisory experience preferred

As the leading employer in our industry in the Pacific Northwest, Seattle Genetics is proud to offer a competitive total compensation package as well as a comprehensive benefits program designed to support the whole lives of our employees and their families. Benefits include medical, vision and dental coverage, group and supplemental life insurance, 401(k) with company match, tuition reimbursement, relocation assistance and much more. To learn more about Seattle Genetics, please visit www.seattlegenetics.com.

Seattle Genetics is an equal opportunity employer. All qualified applications will receive consideration for employment without regard to race, age, gender identity, sexual orientation, color, religion, sex, marital status, national origin, protected veteran status, disability status, or any other status protected by federal, state, or local law.

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