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Translational Data Scientist

Novartis – Cambridge, MA

7000 patients, 1200 sites, 40 countries, over 100 clinical studies led by Translational Medicine last year.
As a member of the Quantitative Sciences & Innovation (QSI) unit in Biomarker Development, you will join Novartis clinical trial teams to speed new medicines into the clinic across one of the industrys largest and most innovative portfolios. By integrating large-scale genomic and biomarker profiles from First-In-Human through Phase III clinical trials, you will investigate disease heterogeneity, drug efficacy, and patient safety at molecular resolution to advance trials in new indications and patient populations.
What youll be doing:
Your responsibilities will include, but are not limited to:
  • Conceive, design, and execute exploratory analyses as Lead Biomarker Analyst within First-In-Human, Phase I-III clinical trials, applying advanced analytical methods as required.

  • Provide Statistical Genetics subject matter expertise and analysis solutions to inform patient stratification and enrichment strategies.

  • Participate in and lead cross-functional biomarker collaborations with Discovery and Development partners to support target selection and registration activities.

  • Work expeditiously as a member of cross-functional clinical trial teams with diverse membership and expertise.

EEO Statement

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status.

Minimum requirements

What you will bring to the role:
  • PhD or MD or equivalent experience in statistical genetics, bioinformatics, biostatistics, computational biology, machine learning, data science or related field.

  • Three or more years of experience in analyzing large biological datasets in a drug discovery/development or relevant academic setting

  • Expert knowledge of statistical programming in R. Working experience with Python or similar scripting programming language a must.

  • Expertise in human genetics or molecular epidemiology, with a strong grasp of genomic approaches, technologies, and analytics to inform clinical trial design and enrichment, e.g. GWAS/RVAS/PheWAS.

  • Experience with causal inference and/or graphical methods highly desirable, e.g. Mendelian Randomization.

  • Solid understanding of biostatistics and machine learning.

What Novartis can offer you?
Yes, we offer exceptional benefits and competitive salaries. However, we can offer more. Here you will:
  • Be part of a world class organization dedicated to developing new therapeutics for un-met medical needs

  • Join an organization committed to your professional development and advancement

  • Apply the latest technologies to clinical research and development

Why consider Novartis?
927 million. That is how many lives our products touched in 2017. And while we are proud of that fact, in this world of digital and technological transformation, we must also ask ourselves this: how can we continue to improve and extend even more peoples lives?
We believe the answers are found when curious, courageous and collaborative people like you are brought together in an inspiring environment. Where you are given opportunities to explore the power of digital and data. Where you are empowered to risk failure by taking smart risks, and where people who share your determination to tackle the worlds toughest medical challenges surround you.
We are Novartis. Join us and help us reimagine medicine.

Division

NIBR

Business Unit

Translational Medicine

Country

USA

Work Location

Cambridge, MA

Company/Legal Entity

NIBRI

Functional Area

Research & Development

Job Type

Full Time

Employment Type

Regular

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