Scientist III

This position requires a talented and highly motivated scientist to immediately support a high priority project within the Cell and Gene Therapy R&D team.
The role will focus on the optimization and development of specific protocols for genetic engineering of t-cells, NK cells and/or hematopoietic stem cells using CRISPR gene-editing tools and new delivery technology platforms.
The ideal candidate will have knowledge and experience in cell therapy process development.
They will also be able to troubleshoot and integrate instruments across workflows for large-scale culture needs. Additionally, an adaptable and flexible scientist that can work quickly in a fast-paced environment is highly preferred.

Primary Responsibilities

Critically design, plan and independently execute experiments while adhering to project requirements and deadlines
Optimize protocols for genetic modification of immune and stem cells with CRISPR based tools in support of customer needs
Setup and perform complex flow cytometry characterization assays to identify specific cell populations
Maintain detailed, organized notebook and experiment write-ups that can be quickly referenced and referred to
Utilize Design of Experiment to promptly analyze assay results and creatively prepare presentations to communicate scientific findings, conclusions and next steps

Knowledge, Skills, Abilities

Demonstrate a sense of urgency, strong drive and can-do attitude to take on new tasks with initiative and intensity
Excellent verbal and written communication skills
Highly developed presentation skills to communicate results and needs to both internal and external team members
Aseptic cell culture of primary cells and/or immune cell experience is required
Experience with automated isolation/purification of various primary blood cell types
CRISPR based assay development for both knock-out and knock-in optimization
Experience with Attune NxT Flow Cytometer is preferred but not required
Education Requirements
PhD in cellular biology, immunology or another relevant discipline with 1-2 years of industry experience, or
M.S. degree in relevant discipline with 3-4 years of industry experience